PNPLA3 and type 2 diabetes mellitus: The risk alleles of the two strongest steatogenic variants, PNPLA3 rs738409 (I148M) and TM6SF2 rs58542926 (E167K), were associated with a small increase in the risk of T2D (allelic ORs 1.04, 95% c.i. 1.01–1.07 and 1.14, 95% c.i. 1.10–1.19, respectively).