Although no SNPs reported in the GPR1 or CMKLR1 gene implicate them with obesity and metabolic syndrome, there is a positive correlation found between common genetic variants in the RARRES2 gene (SNP rs17173608 and rs10278590) with increased visceral adiposity (Müssig et al., 2009). Here, RARRES2 is linked to obesity due to melanocortin 4 receptor deficiency.