The present meta‐analysis found a significant relationship between ALDH2 gene G487A polymorphism and CAD under allele (OR: 1.830), recessive (OR: 1.920), dominant (OR: 1.593), homozygous (OR: 2.280) and heterozygous genetic models (OR: 3.330) in the Chinese population. The gene discussed is ALDH2; the disease is coronary artery disorder.