Similar results are also observed when citreoviridin (a mycotoxin and potent inhibitor of mitochondrial ATPase) is used in HepG2 cells, YM155 (a small molecule suppressor of Survivin) in prostate cancer cells and cyathin Q (a new cyathane type diterpene) in HCT116 cells 24, 25, 27. The gene discussed is ATP5F1E; the disease is Familial prostate cancer.