The data represent the frequencies of alleles, genotypes and haplotypes for single nucleotide polymorphisms (SNPs) rs2279590 and rs1532278 in human clusterin gene (CLU) associated to Alzheimer's diseases in previously published genome-wide and candidate genes association studies [1], [2], [3], [4], [5]. This evidence concerns the gene CLU and early-onset autosomal dominant Alzheimer disease.