RBM10 and neoplasm: This functional RBM10 dichotomy was recognized by Rodor et al21 who noted RBM10 may have cell type and/or species specific roles, but was directly tackled recently by our group: we proposed a working model that describes how the regulation of RBM10 expression determines function, whether tumor suppressive or tumor promoting.21 Notably, this working model contains many hypotheses that remain to be tested.