In addition, correlational studies from human tissues support an apoptosis‐promoting role for RBM10, as RBM10 mRNA expression in breast cancer samples correlated with increased mRNA expression of BAX, a proapoptotic protein, and TP53, a tumor suppressor protein with transcriptional activity.43 Unexpectedly, however, the latter study also correlated RBM10 expression with increased mRNA expression of VEGF, a potent promoter of angiogenesis.43 This evidence concerns the gene RBM10 and breast carcinoma.