MECP2 and Rett syndrome: In humans, mutations of the transcriptional regulator methyl‐CpG‐binding protein 2 (MeCP2) gene lead to a neurodevelopmental disorder called Rett syndrome, which is characterized by irregular breathing pattern and blood gas instability (Southall et al., 1988; Viemari et al., 2005; Ramirez, Ward, & Neul, 2013).