NEFL and amyotrophic lateral sclerosis: Furthermore, the assessment of neurofilament light-chain in the cerebrospinal fluid (CSF) of another cohort of ALS and ALSci patients (Table 1; cohort 3) revealed comparable levels (ALS = 7950 ± 2030 pg/ml, ALSci = 11,068 ± 3073 pg/ml.