APOE and myocardial infarction: In contrast, hypomorphic E mice deficient in SR-B1 with low expression of an allelic variant of mouse apoE (SR-B1−/−/ApoeR61h/h), have a normal life span on a normal chow diet, but die prematurely from repeated spontaneous myocardial infarction as a result of atherothrombosis after 4–8 weeks on a Paigen diet8.