In Fig. 6, levels of the IL-1β precursor had significantly increased, by 2.84-, 2.44- and 2.52-fold in mice with low-dose infection, by 2.46-, 2.68- and 2.95-fold in mice with medium-dose infection and by 2.85-, 2.44- and 2.52-fold in high-dose infection group at 8, 16 and 20 wpi, respectively (Fig. 6c). Here, IL1B is linked to infection.