Although it is well accepted that overt hypothyroidism and overt hyperthyroidism have a deleterious impact on pregnancy, recent studies indicate that SCH may affect maternal and fetal health, have shown an association of miscarriage or preterm delivery in euthyroid women with positive anti-peroxidase antibodies (TPO Ab) and/or anti-thyroglobulin antibodies (TG Ab) and reported the prevalence and long-term impact of postpartum thyroiditis [1]. This evidence concerns the gene TPO and thyroid gland disorder.