Specifically, the transcript expressions of AKR1C1, S100A2, PLAU, SLC3A2, TBC1D2, and WIZ were decreased, while expressions of TGM2, SLC7A5, and NMI were increased in renal tumors when compared with non-tumorous control samples (Fig 6). The gene discussed is SLC7A5; the disease is kidney neoplasm.