The 9q33.1 deletion was initially reported as a likely benign variant but later reclassified by the genetic testing company as a copy number change of uncertain significance in light of a publication reporting enrichment of deletions involving TRIM32 and ASTN2 in males with neurodevelopmental disorders including ASD, ADHD and anxiety (Lionel et al., 2014). This evidence concerns the gene TRIM32 and Anxiety.