Specific disorders will require more sophisticated exams (angiotensin converting enzyme (ACE) in sarcoidosis [8], complete blood count (CBC) with peripheral smear helping to establish eosinophilia [9] in hypereosinophilic syndromes, serum iron concentrations, total iron-binding capacity and ferritin levels in hemocromatosis, immunoglobulin free light κ, λ chain testing, and serum and urine immunofixation in amyloidosis, etc.). The gene discussed is ACE; the disease is amyloidosis.