However, human patients lacking the IL-17A receptor do not suffer from mycobacterial infections (20), whereas patients with mutations in RORC lack the Th1* subset able to produce both IFN-γ and IL-17 (patients do not produce IL-17 A and IL-17 F) and suffer from both Mycobacterium and Candida infections (23). This evidence concerns the gene IFNG and candidiasis.