However, serum GP73 levels are dramatically elevated in context of various types of liver disease such as viral infection (HBV, HCV), alcohol-induced liver disease (Kladney et al., 2002), cirrhosis (Iftikhar et al., 2004), or HCC (Gao et al., 2015; Sai et al., 2015; Zhang et al., 2016). The gene discussed is GOLM1; the disease is viral infectious disease.