It has been shown that CD36 activity may also influence the metastatic properties of tumor cells (Pascual et al., 2017), implicated in the incorporation of oxidized LDL in macrophages during atherosclerotic plaque formation (Park et al., 2009) and has been associated to Alzheimer disease (Šerý et al., 2017). Here, CD36 is linked to early-onset autosomal dominant Alzheimer disease.