Among the strategies that can minimize the negative impact of insulin resistance, regular physical exercise emerges as a non-pharmacological strategy offering health benefits for the general population (Garber et al., 2011) and acts directly on the regulation of glucose metabolism from acute and chronic effects, activating the insulin signaling pathway and the independent pathway of insulin action (Lima et al., 2009; Pauli et al., 2009). Here, INS is linked to Insulin resistance.