FLT3 and acute myeloid leukemia: The UK MRC AML15 clinical trial (ISRNCTN17161961) & UK NCRI AML17 (ISRNCTN55675535) involving five hundred patients in the United Kingdom, Denmark, and New Zealand showed no significant differences in the 5-year overall survival and 5-year relapse-free survival when added to the standard chemotherapy for newly diagnosed FLT3 mutated AML (Knapper et al., 2017).