Moreover, HNSCC patients with both TP53 mutations and high levels of FOXM1 expression (n = 177) had lower survival rates than the patients with wild-type TP53 (n = 151) or with mutant TP53 and low levels of FOXM1 expression (n = 177) (Fig. 7j). Here, TP53 is linked to head and neck squamous cell carcinoma.