TF and cataract: In the proband’s parents (I:1, I:2) and siblings (II:1, II:3) variable degrees of mild bilateral cataracts (Fig. 1B) were observed, with elevated, but significantly lower levels of circulating ferritin compared to the proband (576 μg/L, 586 μg/L, 460 μg/L, and 661 μg/L respectively), with normal levels of serum iron and transferrin saturation.