COMT and carcinoma: Specific to SKBR3/HER2+ cells, on the other hand, were the receptor tyrosine kinase ERBB2, growth factor receptor bound protein (GRB7), breast carcinoma amplified sequence (BCAS1), S100 calcium binding protein P (S100P), aldehyde dehydrogenase 2 (ALDH2), and catechol-O-methyltransferase (COMT).