From the pathophysiological point of view, itis implicit that higher levels of BNP correlate with greater ventricular parietaltension, myocardial ischemia and its secretion and mechanism of action have acardioprotective effect in the attempt to promote systemic and coronary arterialvasodilation, as well as venodilation with reduction of pre and post loading andimprovement of cardiac index[9,23]. Here, NPPB is linked to myocardial ischemia.