Findings from our previous work demonstrated that glyceraldehyde-3-phosphate dehydrogenase (Gapdh), a commonly used housekeeping gene, revealed reduced expression when cerebellar granule neurons (CGNs) were treated with CSF obtained from distinct clinical types of MS and Neuromyelitis optica (NMO) patients [42]. The gene discussed is GAPDH; the disease is myeloid sarcoma.