For example, apigenin can inhibit EMT to circumvent tumor migration in human hepatocellular carcinoma (HCC) cells by inactivating the NF-κB/Snail cascades.168 In addition, galangin, a flavonoid that shows anticancer properties, can also inhibit cell invasion by restraining EMT in human renal cancer cells.169 Unlike apigenin, galangin induces ROS accumulation that leads to cell death. This evidence concerns the gene SNAI1 and neoplasm.