ALB and neoplasm: Human serum albumin (HSA) is one of the major plasma proteins and an ideal drug delivery carrier.43–47 Meanwhile, HSA is ready to accumulate in malignant and inflammatory tissues, which are lack of lymphatic drainage, indicating that HSA has a certain feature of tumor targeting.48 Consisting of scFv–HSA fusion antibodies as guiding molecules, the half-life of ADCs can be increased and the in vivo tumor targeting can be enhanced to a certain extent.