CD8A and parasitic infectious disease: Thus, cell-mediated immunity, particularly CD8+ T cells, plays a crucial role in controlling parasite infection.2 Considering this scenario, we believe that a multicomponent vaccine is appropriate in order to increase the breadth of the immune response triggered by vaccination. Our results highlight the importance of designing chimeric molecules in multicomponent vaccines a fact that must be considered not only to reduce production costs but also to seek for an improvement in the magnitude and quality of the immune response elicited by each component.