These enzymes play a vital role in matrix degradation, inflammation, and tumour cell migration.25 Thus, MMPs are of great interest in terms of tumour-specific drug delivery.26 One example of this is the development of a melittin/avidin conjugate27 and a melittin-MMP-2-LAP28 recombinant adenovirus to increase MMP-2-specific targeting. The gene discussed is MMP2; the disease is neoplasm.