Out of the 14 patients carrying 22q13 deletions and having seizures, 4 were carrying an additional CNV covering a known risk gene for epilepsy: KCNT1 (OMIM: 608167), MYT1L (OMIM: 613084), DEAF1 (OMIM: 602635) and SLC25A22 (OMIM: 609302) (Fig. 4, Supplementary Fig. 4). The gene discussed is KCNT1; the disease is epilepsy.