FAM107A has been previously associated with various cancers, including neuroblastoma,52 renal cell carcinoma53,54 and fibrosarcoma.55 At the same time, the expression of FAM3D in patients’ blood was proposed as an early biomarker for colon cancer.56 Our findings extend the growing body of evidence on the roles of ncRNAs in HNSCs. This evidence concerns the gene FAM3D and malignant colon neoplasm.