There was no significant difference in IL-10 mRNA levels induced by AF2122 and G18 infection up to 24 h, but from 6 h onwards IL-10 mRNA levels returned to baseline levels more rapidly following AF2122 infection than G18, resulting in significantly higher levels of IL-10 mRNA at 48 hpi and 72 hpi in bMDM infected with G18. The gene discussed is IL10; the disease is infection.