Focusing on the PVT1 chromosome interval representing circPVT1, we did not observe any difference between tumor samples with either FAT1 or CDKN2A mutations and those with an intact FAT1 or CDKN2A gene, which were both up-regulated in comparison to non-tumoral samples (Additional file 1: Figure S1a, b). Here, PVT1 is linked to neoplasm.