We assume that other systemic inflammatory response parameters (such as NLR, PNI, mGPS, CRP, CAR) can not represent the LCC and RCC inflammatory difference is that hypoalbuminemia reflects a malnutrition but not inflammatory reaction [47] and that is why the CAR, mGPS and PNI were not the representative index between the LCC and the RCC. The gene discussed is CRP; the disease is Hypoalbuminemia.