In addition, PATZ1 interacting protein RNF4 is expressed in spermatocytes but not in all tumors including SEs, the highly malignant embryonal carcinomas, YST, and mixed GCTs suggesting that the lack of RNF4 expression could play a role in the progression of testicular tumors [40–41]. The gene discussed is RNF4; the disease is neoplasm of testis.