SPARC and colorectal cancer: The wound healing and CCK-8 assays showed si-SPARC significantly inhibited colorectal cancer cell proliferation and migration, hsa-miR-29c-3p inhibitor had the opposite effect, however, in the cells co-transfected with hsa-miR-29c-3p inhibitor and the si-SPARC, hsa-miR-29c-3p inhibitor didn’t have significantly effect in cell proliferation and migration (Figure 10C, 10H, 10I).