CEACAM1 and colorectal carcinoma: In addition, patients exhibiting high expression of both CEACAM1 and CEACAM6 genes had a much poorer outcome than those with high CEACAM1 and low CEACAM6 expression (Figure 4F, blue versus yellow line for T3 and T4 stages; Supplementary Figure 6F, blue versus yellow line for all stages), confirming the importance of other CEACAM family members in CRC metastasis.