Using univariate (Supplementary Table 1) and multivariate (Table 1) linear regression models, we evaluated associations between the CEACAM1, CEACAM5, CEACAM6 and EPHA2 mRNA levels in tumors and clinicopathological parameters relative to age, gender, primary tumor site presentation, primary lymphatic presentation (i.e. a yes/no/unknown indicator whether a lymph node assessment was performed at the primary presentation of disease), lymphatic and venous invasion. Here, EPHA2 is linked to neoplasm.