GPNMB and neoplasm: Quantification of tumor uptake at 4 and 7 days p.i. determined that [89Zr]DFO-CR011 had a mean SUV of 2.9 ± 0.6 in the gpNMB-positive xenograft versus 1.6 ± 0.5 in the gpNMB-negative model (P < 0.05) at 4 days p.i. (Figure 2B).