Supplementary Figure 10 confirms the membrane and cytoplasmic staining of gpNMB although quantification using this technique was not performed due to the heterogeneous expression of gpNMB within each PDX tumor sample. Thus, we simplified our correlative analysis to total gpNMB expression using ELISA. Despite the heterogeneity of gpNMB expression, a positive correlation was determined between [89Zr]DFO-CR011 tumor uptake in vivo and total gpNMB expression ex vivo (r = 0.79, Figure 4B). This evidence concerns the gene GPNMB and neoplasm.