MPL and cancer: The cancer-relevant function of ATXN2L is unknown, but Meunier et al [28] reported that it interacts with the thrombopoietin receptor MPL, and Kaehler et al [30] found ATXN2L in a complex together with the RNA helicase DDX6, the poly(A)-binding protein, and ataxin-2 indicating that ATXN2L is involved in cellular RNA processing.