In the present study, we show that ABR induces the transcription factor C/EBPα and thereby increases the expression of G-CSF-R, M-CSF-R and miR-223 (Figure 4A–4F) suggesting that ABR expression could have a significant role in myeloid differentiation and in leukemia through induction of the CEBPA gene and its target genes. The gene discussed is CSF3R; the disease is leukemia.