IL1B and neoplasm: At a ∼250mm3 tumor volume, mice were divided into 4 groups intraperitoneally injected with: vehicle, Anakinra (human grade IL-1β antagonist; IL-1ra, 10mg/kg [49]), SB265610 (CXCR2 inhibitor, 2mg/kg [14]) or both (same concentrations) for 4 consecutive days.