For instance, Cao et al. [19] revealed that downregulation of lncRNA CASC2 by microRNA-21 increased the proliferation and migration of renal cell carcinoma cells; Zhang et al. [20] illustrated that Antisense lncRNA FOXC2-AS1 promoted doxorubicin resistance in osteosarcoma by increasing the expression of FOXC2; and Liu et al. [21] related that epigenetic silencing of miR-218 by the lncRNA CCAT1, acting via BMI1, promoted an altered cell cycle transition in the malignant transformation of HBE cells induced by cigarette smoke extract. This evidence concerns the gene FOXC2 and osteosarcoma.