WNT5A and breast cancer: Interestingly, Wnt/β-catenin genes, reported as PRMT5 targets in leukemic stem cells (Jin et al., 2016, Tee et al., 2010), could not be validated by qPCR (Wnt5A, PRICKLE2), implying that the mechanisms by which PRMT5 regulates stem cells in breast cancer and leukemia are different.