ZEB2 and neoplasm: The activity of the Zinc finger E-box-binding homeobox 2 (ZEB2) protein, a factor highly expressed in GBM patients with fast tumor progression, also appears to be positively correlated to β-catenin expression [113], while the factor SRY-Box 7 (SOX7) could probably act as a repressor of the Wnt/β-catenin pathway [114].