Recently, for example, it has been reported an unexpected role of beta-catenin in determining the anti-proliferative behaviour of these territories: in particular, by stimulating the production of a microRNA (miR-302), which targets cyclin D1, beta-catenin reduces stemness properties in some tumor cells; this effect seems to be induced by a protein known as Dedicator of cytokinesis protein 4 (DOCK4) [207]. The gene discussed is CTNNB1; the disease is neoplasm.