TNF and glioblastoma: In some GBM forms, NF-κB function has been correlated with iperactivation of epidermal-(EGFR) and platelet-derived-(PDGFR) growth factor receptors [117,118]; moreover, NF-κB was associated with mesenchymal phenotype acquisition in response to tumor necrosis factor (TNF) stimulation in cultures of GSC derived from GBM patient [119].