It is of note that transmembrane protein 79/mattrin (Tmem79/Matt), a five-transmembrane protein of lamellar bodies, is essential in the lamellar body secretory system and that flaky tail (Mattma/maFlgft/ft) mice and Tmem79 (ma/ma) mice with ma mutation exhibit spontaneous AD-like dermatitis [44, 57]. The gene discussed is TMEM79; the disease is skin disorder.