In the present report, we compared the expression of calcium-binding proteins and somatostatin in the retrobulbar and cortical anterior and poster divisions of the AON (the anterior olfactory nucleus, retrobulbar (AONrb), anterior olfactory nucleus, cortical anterior (AONca) and anterior olfactory nucleus, cortical posterior (AONcp), respectively) in PD and control cases. This evidence concerns the gene SST and Parkinson disease.