Considering the involvement of FMRP in mRNA transport in aRGCs (Pilaz et al., 2016; Pilaz and Silver, 2017), it would be interesting to understand if and how impaired mRNA transport in aRGCs contribute to the etiology of FXS and ASD (for an extensive discussion on the link between FXS, ASD, neural progenitors and cortical neurogenesis refer to Callan and Zarnescu, 2011; Packer, 2016; Marchetto et al., 2017 and references therein). This evidence concerns the gene FMR1 and fragile X syndrome.