TEX11 and Infertility: Thus, it is critical for synaptonemal complex and chiasma formation during chromosomal cross‐over.103, 104, 105, 106 The protein is highly conserved and functionally uniform across species.103 It was reported that male Tex11‐knockout mice showed infertility, with azoospermia that was caused by meiotic arrest.107 In 2015, a whole‐genome array comparative genomic hybridization screening study that involved 15 patients with azoospermia was conducted.108 A recurrent 99 kb TEX11 intragenic deletion (Xq13.2) was identified in two unrelated patients.