Interestingly, while the numbers were too small for formal analyses, examination of clinical characteristics revealed that HOXB13 G84E variant carriers that transcribed the variant allele (PcTas12–3 and PcTas72–6) had lower tumour grades and Gleason scores (GS) than variant carriers that did not transcribe the variant allele. Here, HOXB13 is linked to neoplasm.