Figure 6B–D confirms the cell-specific changes in phosphorylation detected in both HNSCC cell lines i.e. JNK (pT183/pY185) activation in FaDu cells, downregulation of phosphoAMPKα (Thr172) in UT-SCC-42B, and activation of pAKT (Ser473) and ERK (T185/Y187) in UT-SCC-42B cells. Here, MAPK8 is linked to head and neck squamous cell carcinoma.