Finally, 31 studies of Asian population were met the inclusion criteria6–9,15–23,28–42, 13 studies of them evaluated the association of mTOR rs2295080 with cancer risks6–9,15–23, 10 studies determined the SNP rs2536 of mTOR gene and cancer susceptibility7,15–18,22,23,28–30, 16 publications were pTEN rs701848 polymorphism7,15,27,31–42, 6 reports studied the AKT1 rs2494750 SNP7,15,23–27 and 3 reports determined AKT1 rs2494752 SNP19,26,27. The gene discussed is PTEN; the disease is cancer.